Protein_Dna_Binding

Protein_Dna_Binding

Inside cells, some DNA is wound into tight packets, known as nucleosomes. Special enzymes bind to these compact packages of genetic material, helping to activate genes. But just how the crucial binding happens in three-dimensional space was unclear.

“For years, the research community has been at an impasse,” Frank Pugh, director of the Penn State Center for Eukaryotic Gene Regulation, said in a prepared statement. “We were limited to only speculating how cellular proteins

might bind to the nucleosome.”

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